Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.64 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024563 | 0.88 | CYP19A1 (0.82) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL11352983 | 0.85 | CYP19A1 (0.60) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL11804787 | 0.84 | CYP19A1 (0.66) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL11353278 | 0.84 | CYP19A1 (0.70) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| Lombazole SCHEMBL829388 | 0.81 | CYP17A1 (0.73) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL738495 | 0.78 | CYP19A1 (1.00) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL9364497 | 0.78 | CYP19A1 (0.69) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL11644939 | 0.77 | CYP19A1 (0.68) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL11365302 | 0.77 | CYP19A1 (0.71) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| Bromide SCHEMBL28170216 | 0.77 | CYP19A1 (0.96) | CYP19A1CYP17A1MEN1NR1I2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241175-B1 | TOPICAL ANTIMICROBIAL PHARMACEUTICAL COMPOSITION COMPRISING A SILVER COMPOUND AND AN AZOLE | SMITH & NEPHEW plc (GB) | 1990-12-27 | — | — | EP | claimed |
| JP-60061518-A | — | — | None | — | — | JP | disclosed |
| JP-S6061518-A | GELATINOUS EXTERNAL COMPOSITION | HISAMITSU PHARMACEUT CO INC | 1985-04-09 | — | — | JP | disclosed |