SCHEMBL10456554

SCHEMBL10456554

C=CO[Si](C)(C=C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94078 0.83 ESR1 (0.35) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL365231 0.81 ESR1 (0.34) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL6889166 0.81 ESR1 (0.34) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL296246 0.81 ESR1 (0.34) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL13835936 0.80 ESR1 (0.37) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL12032189 0.79 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL28879222 0.79 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL9900064 0.79 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL29227821 0.79 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL10456261 0.78 ESR1 (0.35) ESR1ESR2ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0165806-B1 SILYLATED VINYL ALCOHOL POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-29 EP disclosed
EP-0165806-A2 Silylated vinyl alcohol polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-27 EP disclosed
US-4544724-A REACTING ETHENOXYSILANE AND ALDEHYDE, POLYMERIZATION, THEN HYDROLYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-01 US disclosed