SCHEMBL9900064

SCHEMBL9900064

C=C[Si](C)(O[Si](O[Si](C)(C=C)c1ccccc1)(O[Si](C)(C=C)c1ccccc1)O[Si](C)(C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94078 0.91 ESR1 (0.35) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL6889166 0.89 ESR1 (0.34) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL12032189 0.88 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL28879222 0.88 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL15544196 0.86 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL13038467 0.86 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL842155 0.86 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL31344407 0.86 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL19398250 0.84 ESR1 (0.31) ESR1ESR2
SCHEMBL681999 0.82 ESR1 (0.31) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2649114-A1 SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS Dow Corning Corporation (US) 2013-10-16 EP disclosed
EP-2649131-A1 SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS Dow Corning Corporation (US) 2013-10-16 EP disclosed
EP-2649113-A1 SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS Dow Corning Corporation (US) 2013-10-16 EP disclosed
US-20130256742-A1 Siloxane-Compositions Including Metal-Oxide Nanoparticles Suitable For Forming Encapsulants DOW CORNING CORPORATION (US) 2013-10-03 US disclosed
US-20130256741-A1 Siloxane Compositions Suitable For Forming Encapsulants DOW CORNING CORPORATION 2013-10-03 US disclosed
WO-2012078582-A1 SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS DOW CORNING CORPORATION (US) 2012-06-14 WO disclosed
WO-2012078617-A1 SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS DOW CORNING CORPORATION (US) 2012-06-14 WO disclosed
WO-2012078594-A1 SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS DOW CORNING CORPORATION (US) 2012-06-14 WO disclosed