SCHEMBL10456740

SCHEMBL10456740

CCC(OC)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CES1 P23141 10/20 0.59
▸ SRC P12931 1/20 0.46
▸ CES2 O00748 8/20 0.43
▸ KCNN4 O15554 1/20 0.42
▸ TSHR P16473 1/20 0.41
▸ LMNA P02545 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CTNNB1 P35222 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868096 0.88 CES1 (0.51) CES1SRCCES2KCNN4TSHR
SCHEMBL36097 0.86 CES1 (0.59) CES1SRCCES2KCNN4TSHR
SCHEMBL7911425 0.85 CES1 (0.49) CES1SRCCES2KCNN4LMNA
SCHEMBL2729130 0.84 CES1 (0.46) CES1CES2KCNN4TSHRALDH1A1
SCHEMBL2190401 0.83 CES1 (0.56) CES1SRCCES2KCNN4TSHR
SCHEMBL18901487 0.82 CES1 (0.44) CES1CES2KCNN4ALDH1A1MAPT
SCHEMBL135045 0.82 CES1 (0.54) CES1SRCCES2KCNN4TSHR
SCHEMBL11091632 0.81 CES1 (0.53) CES1SRCCES2KCNN4TSHR
SCHEMBL6529359 0.81 MAPT (0.48) CES1KCNN4LMNAMAPTCYP2C19
SCHEMBL6885914 0.80 CES1 (0.44) CES1SRCCES2TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10754199-B2 Liquid crystal composition, liquid crystal display device using the liquid crystal composition, and method of manufacturing the liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 — — US disclosed
US-20190121178-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE USING THE LIQUID CRYSTAL COMPOSITION, AND METHOD OF MANUFACTURING THE LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-25 — — US disclosed
US-9518223-B2 Liquid crystal composition and liquid crystal display including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-12-13 — — US disclosed
US-9518223-B2 Liquid crystal composition and liquid crystal display including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-12-13 — — US disclosed
US-20160200978-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-14 — — US disclosed
US-20160200978-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-14 — — US disclosed
US-4902724-A Photocurable acrylic coating composition GENERAL ELECTRIC COMPANY (US) 1990-02-20 — — US disclosed
EP-0274596-A2 Aromatic carbonate resin articles coated with a photocured acrylic coating GENERAL ELECTRIC COMPANY (US) 1988-07-20 — — EP disclosed
US-4597918-A Method of removing soft contact lenses from the mold SUNSOFT CORPORATION 1986-07-01 — — US disclosed
US-4578230-A Method of contouring the edge of contact lenses SUNSOFT CORPORATION 1986-03-25 — — US disclosed
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