Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518341 | 0.92 | FLT3 (0.38) | SIRT2FLT3TYRO3MERTKGAS6 | |
| SCHEMBL1414901 | 0.89 | SIRT2 (0.40) | SMN1; SMN2L3MBTL1SIRT2CYP11B1CYP11B2 | |
| SCHEMBL1735234 | 0.87 | CYP11B1 (0.37) | SIRT2CYP11B1CYP11B2NMBR | |
| SCHEMBL1736018 | 0.85 | SIRT2 (0.36) | L3MBTL1SIRT2CYP11B1CYP11B2 | |
| SCHEMBL8865971 | 0.85 | KCNH2 (0.42) | SIRT2CES1 | |
| SCHEMBL9489847 | 0.83 | SIRT2 (0.40) | SIRT2CYP11B1CYP11B2NMBR | |
| SCHEMBL4030251 | 0.82 | SIRT2 (0.40) | SIRT2CYP11B1CYP11B2NMBR | |
| SCHEMBL1483017 | 0.82 | SIRT2 (0.39) | L3MBTL1SIRT2CYP11B1CYP11B2CES2 | |
| SCHEMBL1040045 | 0.81 | CYP11B1 (0.41) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL9789313 | 0.81 | SIRT2 (0.42) | SMN1; SMN2SIRT2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194984-B1 | DERIVATIVES OF IMIDAZOLE, THEIR PREPARATION AND UTILISATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | CONTINENTAL PHARMA, INC. (BE) | 1990-04-04 | — | — | EP | disclosed |
| US-4738979-A | ADRENERGIC RECEPTORS; ANTI-CONVULSIVE DRUG; TREATMENT OF METABOLIC AND NEUTRAL DISORDERS | G. D. SEARLE & CO. (US) | 1988-04-19 | — | — | US | disclosed |