Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457151 | 0.92 | HPGD (0.39) | FLT3TYRO3MERTKGAS6SIRT2 | |
| SCHEMBL1736018 | 0.88 | SIRT2 (0.36) | SIRT2 | |
| SCHEMBL1414901 | 0.86 | SIRT2 (0.40) | SIRT2 | |
| SCHEMBL1735234 | 0.85 | CYP11B1 (0.37) | SIRT2 | |
| SCHEMBL8865971 | 0.83 | KCNH2 (0.42) | SIRT2CES1 | |
| SCHEMBL9489847 | 0.81 | SIRT2 (0.40) | SIRT2 | |
| SCHEMBL4030251 | 0.80 | SIRT2 (0.40) | SIRT2 | |
| SCHEMBL1483017 | 0.80 | SIRT2 (0.39) | SIRT2CES2CES1 | |
| SCHEMBL7262693 | 0.79 | SIRT2 (0.32) | SIRT2 | |
| SCHEMBL1040045 | 0.79 | CYP11B1 (0.41) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |
| CN-1198817-C | N-cimidazolylalkyl) substituted cyclic amines as histamine-H3 agonists or antagonists | SCHERING CORP (US) | 2005-04-27 | — | — | CN | disclosed |
| CN-1323302-A | N-cimidazolylalkyl) substituted cyclic amines as histamine-H3 agonists or antagonists | SCHERING CORP (US) | 2001-11-21 | — | — | CN | disclosed |
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |