Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.57 |
| ▸ | RARB | P10826 | 10/20 | 0.57 |
| ▸ | RARG | P13631 | 9/20 | 0.57 |
| ▸ | RXRB | P28702 | 7/20 | 0.57 |
| ▸ | RXRG | P48443 | 5/20 | 0.57 |
| ▸ | RARA | P10276 | 7/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.53 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459341 | 0.97 | RXRA (0.57) | RXRARARBRARGRXRBRXRG | |
| Zinc Ion SCHEMBL10458187 | 0.92 | RXRA (0.47) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL2128581 | 0.86 | RXRA (0.68) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL29440075 | 0.86 | RXRA (0.68) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL10459342 | 0.84 | RXRA (0.67) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL10458082 | 0.84 | RXRA (0.58) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL10458085 | 0.84 | RXRA (0.67) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL10459708 | 0.82 | RXRA (0.56) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL7756637 | 0.82 | RXRA (0.58) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL7622450 | 0.80 | RXRA (0.53) | RXRARARBRARGRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898864-A | Bicyclic aromatic compounds, a process for their preparation and their use in cosmetics and human and veterinary medicine | L'OREAL (FR) | 1990-02-06 | — | — | US | claimed |
| US-4898864-A | Bicyclic aromatic compounds, a process for their preparation and their use in cosmetics and human and veterinary medicine | L'OREAL (FR) | 1990-02-06 | — | — | US | disclosed |