Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 8/20 | 0.47 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932937 | 0.89 | GAA (0.50) | GAAALOX12CYP2C19SRCCES1 | |
| SCHEMBL12064047 | 0.87 | GAA (0.56) | GAASRCCES1CES2ALDH1A1 | |
| SCHEMBL10471882 | 0.84 | SRC (0.47) | GAAALOX12CYP2C19SRCCES1 | |
| SCHEMBL4556750 | 0.83 | CES1 (0.50) | CYP2C19SRCCES1CES2ALDH1A1 | |
| SCHEMBL10943699 | 0.83 | ALDH1A1 (0.50) | GAACES1CES2ALDH1A1KMT2A | |
| SCHEMBL9617688 | 0.82 | SRC (0.46) | GAAALOX12CYP2C19SRCCES1 | |
| SCHEMBL6692640 | 0.82 | GAA (0.48) | GAAALOX12CYP2C19SRCCES1 | |
| SCHEMBL452703 | 0.81 | CES1 (0.49) | GAAALOX12CYP2C19SRCCES1 | |
| SCHEMBL6698931 | 0.80 | GAA (0.54) | GAAALOX12CYP2C19SRCCES1 | |
| SCHEMBL9821868 | 0.80 | GAA (0.47) | GAAALOX12CYP2C19SRCCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181227-A1 | POLYMERIC FUNCTIONAL MEMBRANE FOR REMOVING NITRATE IONS, PRODUCTION METHOD THEREFOR, SEPARATION MEMBRANE MODULE, AND ION EXCHANGE DEVICE | Fujifilm Corporation (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-4902725-A | Photocurable acrylic coating composition | GENERAL ELECTRIC COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0274595-A2 | Aromatic carbonate resin articles coated with a photocured acrylic coating | GENERAL ELECTRIC COMPANY (US) | 1988-07-20 | — | — | EP | disclosed |