Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | DCK | P27707 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454009 | 0.85 | KDM4E (0.45) | TSHRMAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10717739 | 0.82 | TSHR (0.46) | TSHRCA12CA1CA9ALDH1A1 | |
| SCHEMBL25526174 | 0.82 | PTGS1 (0.46) | TSHRCA12CA1CA9ALDH1A1 | |
| SCHEMBL1710102 | 0.81 | INPPL1 (0.43) | TSHRMAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL16942933 | 0.79 | TSHR (0.44) | TSHRSLC6A4SLC6A2SLC6A3APP | |
| SCHEMBL14176650 | 0.79 | NR5A1 (0.50) | TSHRPDIA6 | |
| SCHEMBL7524809 | 0.78 | KDM4E (0.53) | ALDH1A1MAPTKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL14015790 | 0.78 | NR5A1 (0.53) | TSHR | |
| SCHEMBL16939066 | 0.78 | NR5A1 (0.53) | TSHR | |
| SCHEMBL20748335 | 0.78 | INPPL1 (0.41) | TSHRCA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |