Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13091437 | 0.85 | HRH3 (0.55) | KDM4ECHRNB2CHRNA4HRH3LTA4H | |
| SCHEMBL14000157 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1HTR7TDP1SMN1; SMN2 | |
| SCHEMBL30343866 | 0.81 | KEAP1 (0.53) | KDM4ECHRNB2CHRNA4HRH3LTA4H | |
| SCHEMBL310630 | 0.81 | KEAP1 (0.53) | KDM4ECHRNB2CHRNA4HRH3LTA4H | |
| SCHEMBL15062039 | 0.81 | KDM4E (0.51) | KDM4EHRH3ALDH1A1HTR7SMN1; SMN2 | |
| SCHEMBL4632018 | 0.81 | KDM4E (0.51) | KDM4ECHRNA4KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL18773673 | 0.81 | KDM4E (0.52) | KDM4ECHRNB2CHRNA4ALDH1A1MAPT | |
| SCHEMBL12139524 | 0.81 | MAPT (0.56) | KDM4ECHRNB2CHRNA4HRH3LTA4H | |
| SCHEMBL17147252 | 0.81 | KDM4E (0.62) | KDM4ECHRNB2CHRNA4ALDH1A1MAPT | |
| SCHEMBL10717739 | 0.79 | TSHR (0.46) | KDM4ELTA4HALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002018037-A2 | GAS VENT FILTER CONSTRUCTION INCORPORATING A HOLLOW FIBER MEMBRANE ASSEMBLY | MILLIPORE CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |