Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034964 | 0.79 | SMN1; SMN2 (0.37) | LMNACYP2C19 | |
| SCHEMBL13811388 | 0.77 | LMNA (0.31) | LMNACYP2C19 | |
| SCHEMBL10458767 | 0.76 | CA1 (0.41) | — | |
| SCHEMBL10582062 | 0.74 | — | — | |
| SCHEMBL10400435 | 0.72 | LMNA (0.36) | LMNACYP2C19 | |
| SCHEMBL478210 | 0.72 | LMNA (0.33) | LMNACYP2C19 | |
| SCHEMBL19102803 | 0.72 | LMNA (0.38) | LMNACYP2C19 | |
| SCHEMBL2462786 | 0.72 | SLC1A3 (0.39) | LMNACYP2C19 | |
| SCHEMBL26367023 | 0.72 | — | — | |
| SCHEMBL11384976 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |