Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805889 | 0.77 | — | — | |
| SCHEMBL10821317 | 0.77 | — | — | |
| SCHEMBL10621311 | 0.77 | — | — | |
| SCHEMBL7289321 | 0.77 | — | — | |
| Bromide SCHEMBL10821115 | 0.76 | ALOX5 (0.40) | ALOX5IDO1TDO2L3MBTL1CES2 | |
| SCHEMBL1992668 | 0.73 | ALOX5 (0.41) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL31556324 | 0.67 | CYP3A4 (0.44) | ALOX5IDO1TDO2L3MBTL1CES2 | |
| SCHEMBL30295390 | 0.67 | ALOX5 (0.47) | ALOX5IDO1TDO2L3MBTL1CES2 | |
| SCHEMBL7827555 | 0.67 | — | — | |
| SCHEMBL1560841 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | claimed |
| US-4388310-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1983-06-14 | — | — | US | claimed |
| US-4298741-A | DETHIAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-11-03 | — | — | US | claimed |
| US-4281002-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-07-28 | — | — | US | claimed |
| US-4277482-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-07-07 | — | — | US | claimed |
| US-4255423-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-03-10 | — | — | US | claimed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | claimed |
| US-4215124-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-07-29 | — | — | US | claimed |
| US-4197402-A | Cephalosporin analogues | SHIONOGI & CO., LTD. (JP) | 1980-04-08 | — | — | US | claimed |
| EP-0002210-A1 | 6- and 6,6- disubstituted-2-substituted-pen-2-em-3-carboxylic acids; processes for their preparation and pharmaceutical compositions containing such compounds | MERCK & CO. INC. (US) | 1979-06-13 | — | — | EP | claimed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | claimed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | claimed |
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0134301-A1 | 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid | MERCK & CO. INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4465687-A | ANTIARTHRITIC AGENT, ENZYME INHIBITOR | MERCK & CO., INC. (US) | 1984-08-14 | — | — | US | disclosed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | disclosed |
| US-3979384-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3974151-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3962231-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |