Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458309 | 1.00 | NLRP3 (0.45) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL10458284 | 0.87 | CA12 (0.57) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL10458283 | 0.87 | CA12 (0.57) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL10458688 | 0.83 | PPID (0.56) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL10458690 | 0.83 | PPID (0.56) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL10456796 | 0.83 | CA12 (0.44) | CA12CA1CA2CA9HDAC1 | |
| SCHEMBL10458705 | 0.83 | CA12 (0.44) | CA12CA1CA2CA9HDAC1 | |
| SCHEMBL10458421 | 0.83 | CA12 (0.49) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL10458351 | 0.82 | SMN1; SMN2 (0.41) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL10458350 | 0.82 | SMN1; SMN2 (0.41) | NLRP3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977272-A | Radiation absorbers | THE STANDARD OIL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4740611-A | N,N'-disubstituted ureas | THE STANDARD OIL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |