Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CDC42 | P60953 | 1/20 | 0.47 |
| ▸ | RAC1 | P63000 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458486 | 0.98 | ELANE (0.51) | ELANETDP1L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL10458087 | 0.88 | CA12 (0.50) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL487471 | 0.86 | CA12 (0.51) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL11996303 | 0.84 | ELANE (0.57) | ELANETDP1L3MBTL1CYP1A2MAPT | |
| SCHEMBL31322986 | 0.84 | ELANE (0.57) | ELANETDP1L3MBTL1CYP1A2MAPT | |
| SCHEMBL10458000 | 0.83 | ELANE (0.50) | ELANETDP1CYP1A2LMNACA2 | |
| SCHEMBL18211356 | 0.82 | ELANE (0.66) | ELANEL3MBTL1PTGS2LMNAMAPT | |
| SCHEMBL10457999 | 0.81 | AKR1C3 (0.51) | ELANETDP1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL10458078 | 0.81 | ESR1 (0.55) | ELANEAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL15701612 | 0.80 | TDP1 (0.46) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935537-A | OXIDIZING ACYLALKYLNAPHTHALENE WITH PEROXIDE, OXIDIZING PRODUCT WITH OXYGEN USING CATALYST CONTAINING COBALT AND BROMINE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4801737-A | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0170273-B1 | PROCESS FOR PRODUCING ACYLOXYNAPHTHOIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0170273-A2 | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-02-05 | — | — | EP | disclosed |