Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CDC42 | P60953 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487471 | 0.98 | CA12 (0.51) | CA12CA9AKR1C3AKR1C2PTGS2 | |
| SCHEMBL10458484 | 0.88 | ELANE (0.50) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL29705954 | 0.87 | CA12 (0.61) | CA12CA9KDM4ETDP1GLA | |
| SCHEMBL5352558 | 0.87 | CA12 (0.61) | CA12CA9KDM4ETDP1GLA | |
| SCHEMBL10458486 | 0.86 | ELANE (0.51) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL11478631 | 0.83 | AKR1C3 (0.71) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL3974361 | 0.83 | CA12 (0.65) | CA12CA9KDM4ETDP1GLA | |
| SCHEMBL30595409 | 0.83 | CA12 (0.65) | CA12CA9KDM4ETDP1GLA | |
| SCHEMBL20414569 | 0.82 | AKR1C3 (0.60) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL12363840 | 0.82 | ABCB11 (0.50) | CA12CA9AKR1C3AKR1C2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935537-A | OXIDIZING ACYLALKYLNAPHTHALENE WITH PEROXIDE, OXIDIZING PRODUCT WITH OXYGEN USING CATALYST CONTAINING COBALT AND BROMINE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4801737-A | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0170273-B1 | PROCESS FOR PRODUCING ACYLOXYNAPHTHOIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0170273-A2 | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-02-05 | — | — | EP | disclosed |