Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31313628 | 1.00 | APP (0.57) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL29067688 | 1.00 | APP (0.57) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL29184950 | 0.84 | LMNA (0.62) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL5935797 | 0.84 | LMNA (0.62) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11148883 | 0.84 | LMNA (0.62) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL27684582 | 0.84 | LMNA (0.62) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1269440 | 0.82 | APP (0.63) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL8744441 | 0.82 | LMNA (0.42) | APPALDH1A1L3MBTL1KDM4ETSHR | |
| Calcium SCHEMBL2689056 | 0.81 | APP (0.61) | APPPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL28038535 | 0.81 | APP (0.61) | APPPKMALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923686-A | Process for the extraction of metal values | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1990-05-08 | — | — | US | disclosed |
| US-4775763-A | PYRIDINE ESTER OR AMIDE FOR HYDROMETALLURGY | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1988-10-04 | — | — | US | disclosed |
| US-4683310-A | RECOVERING METALS FROM ORES | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1987-07-28 | — | — | US | disclosed |
| EP-0057797-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-06-25 | — | — | EP | disclosed |
| US-4525330-A | SOLVENT EXTRACTION USING ESTER-SUBSTITUTED PYRIDINE OF AQUEOUS HALIDE-CONTAINING SOLUTIONS OF COPPER SALTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1985-06-25 | — | — | US | disclosed |
| EP-0057797-A2 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-18 | — | — | EP | disclosed |