Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.53 |
| ▸ | PNMT | P11086 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458242 | 0.85 | IDO1 (0.37) | IDO1TAAR1KCNH2MAOB | |
| SCHEMBL2339683 | 0.84 | IDO1 (0.53) | IDO1PNMTTAAR1MAOBHPGD | |
| SCHEMBL3774965 | 0.83 | IDO1 (0.67) | IDO1PNMTTAAR1MAOBHPGD | |
| SCHEMBL4058386 | 0.82 | IDO1 (0.55) | IDO1PNMTTAAR1MAOBHPGD | |
| SCHEMBL6602229 | 0.81 | IDO1 (0.50) | IDO1PNMTTAAR1MAOBHPGD | |
| SCHEMBL1988193 | 0.80 | IDO1 (0.53) | IDO1PNMTTAAR1MAOBNR4A2 | |
| SCHEMBL6230376 | 0.80 | IDO1 (0.53) | IDO1PNMTTAAR1MAOBHPGD | |
| SCHEMBL11707615 | 0.79 | IDO1 (0.48) | IDO1PNMTTAAR1MAOBHPGD | |
| SCHEMBL9419151 | 0.78 | IDO1 (0.52) | IDO1PNMTTAAR1MAOBHPGD | |
| SCHEMBL10457899 | 0.78 | TAAR1 (0.43) | TAAR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |