Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707615 | 0.95 | IDO1 (0.48) | IDO1CYP3A4CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL2339683 | 0.89 | IDO1 (0.53) | IDO1CYP3A4CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL19055306 | 0.81 | IDO1 (0.50) | IDO1CYP3A4CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL10458646 | 0.81 | IDO1 (0.53) | IDO1CYP3A4CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL23708530 | 0.80 | IDO1 (0.57) | IDO1NR4A2LMNAPNMTMAOA | |
| SCHEMBL4574094 | 0.80 | MAP2K1 (0.39) | IDO1CYP3A4CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL3774965 | 0.80 | IDO1 (0.67) | IDO1NR4A2LMNAPNMTMAOA | |
| SCHEMBL18596661 | 0.79 | IDO1 (0.47) | IDO1CYP3A4CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL2094931 | 0.79 | IDO1 (0.47) | IDO1NR4A2LMNAPNMTMAOA | |
| SCHEMBL4058386 | 0.79 | IDO1 (0.55) | IDO1NR4A2LMNAPNMTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |