⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650829 | 0.74 | — | — | |
| SCHEMBL2799771 | 0.70 | — | — | |
| SCHEMBL27817382 | 0.67 | — | — | |
| SCHEMBL11022151 | 0.67 | — | — | |
| SCHEMBL15768544 | 0.67 | — | — | |
| SCHEMBL2801157 | 0.67 | HRH3 (0.30) | — | |
| SCHEMBL14236955 | 0.65 | CA1 (0.33) | — | |
| SCHEMBL735350 | 0.65 | DNM1 (0.36) | — | |
| SCHEMBL1858554 | 0.65 | — | — | |
| SCHEMBL4270434 | 0.65 | KDM5A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895918-A | DIORGANOPOLYSILOXANE HAVING JUST ONE ALKOXY GROUP AND AT LEAS ONE HYDROLYZABLE LEAVING GROUP TO REACT WITH FREE HYDROXY GROUPS; FAST CURING; STORAGE STABILITY | GENERAL ELECTRIC COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4755578-A | Alkoxy-functional one-component RTV silicone rubber compositions | GENERAL ELECTRIC COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4670532-A | Alkoxy-functional one-component RTV silicone rubber compositions | GENERAL ELECTRIC COMPANY (US) | 1987-06-02 | — | — | US | disclosed |
| US-4593085-A | Polysiloxane | GENERAL ELECTRIC COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0113849-A2 | Alcoxy-functional one-component R.T.V. silicone rubber compositions | GENERAL ELECTRIC COMPANY (US) | 1984-07-25 | — | — | EP | disclosed |