Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463320 | 0.90 | KCNH2 (0.59) | KCNH2PAX8MEN1CYP2J2HRH3 | |
| SCHEMBL10558799 | 0.89 | KCNH2 (0.63) | KCNH2PAX8MEN1CYP2J2HRH1 | |
| SCHEMBL10461861 | 0.88 | KCNH2 (0.70) | KCNH2PAX8MEN1HRH3DRD2 | |
| SCHEMBL10461054 | 0.88 | KCNH2 (0.57) | KCNH2PAX8MEN1CYP2J2HRH3 | |
| SCHEMBL10462896 | 0.88 | HRH1 (0.61) | KCNH2PAX8MEN1CYP2J2HTR2A | |
| SCHEMBL10459137 | 0.88 | KCNH2 (0.59) | KCNH2PAX8MEN1CYP2J2HRH3 | |
| SCHEMBL10460419 | 0.87 | KCNH2 (0.64) | KCNH2PAX8MEN1CYP2J2HRH3 | |
| Hydrochloric Acid SCHEMBL10566177 | 0.87 | KCNH2 (0.61) | KCNH2PAX8MEN1CYP2J2HRH1 | |
| SCHEMBL10460337 | 0.86 | KCNH2 (0.58) | KCNH2PAX8MEN1CYP2J2HRH3 | |
| Hydrochloric Acid SCHEMBL10557968 | 0.85 | KCNH2 (0.57) | KCNH2PAX8MEN1CYP2J2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |