Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10566177 | 0.98 | KCNH2 (0.61) | KCNH2MEN1PAX8HRH1CYP2J2 | |
| SCHEMBL10461861 | 0.91 | KCNH2 (0.70) | KCNH2MEN1PAX8 | |
| SCHEMBL10459137 | 0.91 | KCNH2 (0.59) | KCNH2MEN1PAX8HRH1CYP2J2 | |
| SCHEMBL10463320 | 0.91 | KCNH2 (0.59) | KCNH2MEN1PAX8HRH1CYP2J2 | |
| SCHEMBL10462896 | 0.89 | HRH1 (0.61) | KCNH2MEN1PAX8HRH1CYP2J2 | |
| SCHEMBL10460482 | 0.89 | KCNH2 (0.57) | KCNH2MEN1PAX8HRH1CYP2J2 | |
| SCHEMBL10461054 | 0.89 | KCNH2 (0.57) | KCNH2MEN1PAX8HRH1CYP2J2 | |
| Fumaric Acid SCHEMBL10461083 | 0.88 | KCNH2 (0.62) | KCNH2MEN1PAX8 | |
| Fumaric Acid SCHEMBL10461081 | 0.88 | KCNH2 (0.62) | KCNH2MEN1PAX8 | |
| Oxalic Acid SCHEMBL10461512 | 0.88 | KCNH2 (0.67) | KCNH2MEN1PAX8CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | claimed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |