Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460508 | 0.95 | KCNH2 (0.64) | KCNH2MEN1PAX8HRH3KMT2A | |
| Oxalic Acid SCHEMBL10461512 | 0.91 | KCNH2 (0.67) | KCNH2MEN1PAX8HRH3KDM4E | |
| Oxalic Acid SCHEMBL10459914 | 0.90 | KCNH2 (0.66) | KCNH2MEN1PAX8HRH3KDM4E | |
| SCHEMBL10461861 | 0.89 | KCNH2 (0.70) | KCNH2MEN1PAX8HRH3KMT2A | |
| Oxalic Acid SCHEMBL10461055 | 0.88 | KCNH2 (0.59) | KCNH2MEN1PAX8HRH3KMT2A | |
| SCHEMBL10558799 | 0.88 | KCNH2 (0.63) | KCNH2MEN1PAX8 | |
| Fumaric Acid SCHEMBL10461081 | 0.87 | KCNH2 (0.62) | KCNH2MEN1PAX8KMT2A | |
| Fumaric Acid SCHEMBL10461083 | 0.87 | KCNH2 (0.62) | KCNH2MEN1PAX8KMT2A | |
| SCHEMBL10459137 | 0.87 | KCNH2 (0.59) | KCNH2MEN1PAX8HRH3KMT2A | |
| SCHEMBL16307892 | 0.86 | KCNH2 (0.80) | KCNH2MEN1PAX8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |