Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flunidazole SCHEMBL636164 | 0.89 | MAPK1 (0.59) | EGFRERBB2MAPK1ALDH1A1LMNA | |
| SCHEMBL11845539 | 0.83 | MAPT (0.48) | EGFRERBB2MAPK1ALDH1A1LMNA | |
| SCHEMBL11824972 | 0.79 | EGFR (0.58) | EGFRERBB2ALDH1A1SMN1; SMN2GLA | |
| SCHEMBL2558351 | 0.78 | TYMS (0.47) | EGFRERBB2MAPK1ALDH1A1LMNA | |
| SCHEMBL11834463 | 0.76 | CA1 (0.53) | EGFRERBB2MAPK1ALDH1A1LMNA | |
| SCHEMBL10402051 | 0.75 | MAPK1 (0.44) | EGFRERBB2MAPK1ALDH1A1LMNA | |
| SCHEMBL9711175 | 0.73 | MAPK1 (0.76) | MAPK1ALDH1A1LMNATHRBTSHR | |
| SCHEMBL27831135 | 0.68 | MAPK1 (0.57) | EGFRERBB2MAPK1ALDH1A1LMNA | |
| Metronidazole SCHEMBL29386975 | 0.66 | MAPK1 (0.68) | EGFRERBB2MAPK1ALDH1A1LMNA | |
| Metronidazole SCHEMBL2670090 | 0.66 | LMNA (0.94) | EGFRERBB2MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925951-A | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |