Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10461342 | 0.90 | KMT2A (0.46) | CHRM3CHRM2CHRM1KMT2AKCNA3 | |
| SCHEMBL10460822 | 0.86 | CHRM3 (0.38) | CHRM3CHRM2CHRM1 | |
| SCHEMBL8880121 | 0.81 | CHRM3 (0.56) | CHRM3CHRM2CHRM1KCNA3 | |
| SCHEMBL9372375 | 0.79 | KMT2A (0.50) | CHRM3CHRM2CHRM1KMT2A | |
| SCHEMBL10718310 | 0.73 | CHRM3 (0.54) | CHRM3CHRM2CHRM1KMT2A | |
| SCHEMBL12794687 | 0.73 | CHRM3 (0.61) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3974183 | 0.73 | CHRM3 (0.61) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4756747 | 0.73 | CHRM3 (0.47) | CHRM3CHRM2CHRM1KCNA3 | |
| SCHEMBL8424963 | 0.73 | DRD2 (0.40) | KMT2AKCNA3 | |
| SCHEMBL10316374 | 0.73 | CHRM3 (0.61) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |