Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 11/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480997 | 0.85 | KCNA5 (0.73) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12587918 | 0.85 | KCNA5 (0.73) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL480998 | 0.85 | KCNA5 (0.73) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5541536 | 0.85 | KCNA5 (0.73) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13649151 | 0.83 | KCNA5 (0.73) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1242816 | 0.78 | KCNA5 (0.73) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1243260 | 0.75 | KCNA5 (1.00) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1241166 | 0.74 | KCNA5 (0.81) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1242084 | 0.73 | KCNA5 (1.00) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1242863 | 0.72 | KCNA5 (0.81) | KCNA5KCNH2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |