Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463121 | 1.00 | PPARG (0.48) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10461725 | 1.00 | PPARG (0.48) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10462806 | 1.00 | PPARG (0.48) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10462372 | 0.99 | PPARG (0.49) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10463097 | 0.96 | MCHR1 (0.54) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10461697 | 0.96 | MCHR1 (0.54) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10462396 | 0.96 | MCHR1 (0.54) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10459660 | 0.96 | MCHR1 (0.54) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10461130 | 0.96 | PPARG (0.51) | PPARGMCHR1CYP3A4MEN1USP2 | |
| SCHEMBL10462469 | 0.94 | MCHR1 (0.55) | PPARGMCHR1CYP3A4MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4913837-A | Heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-03 | — | — | US | disclosed |