Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461697 | 1.00 | MCHR1 (0.54) | MCHR1L3MBTL1MAPTRAB9ARARB | |
| SCHEMBL10462396 | 1.00 | MCHR1 (0.54) | MCHR1L3MBTL1MAPTRAB9ARARB | |
| SCHEMBL10459660 | 1.00 | MCHR1 (0.54) | MCHR1L3MBTL1MAPTRAB9ARARB | |
| SCHEMBL10462469 | 0.99 | MCHR1 (0.55) | MCHR1L3MBTL1MAPTRAB9ARARB | |
| SCHEMBL10460099 | 0.96 | MCHR1 (0.57) | MCHR1L3MBTL1MAPTRAB9ACYP3A4 | |
| SCHEMBL10461875 | 0.96 | PPARG (0.48) | MCHR1L3MBTL1MAPTRAB9ACYP3A4 | |
| SCHEMBL10461725 | 0.96 | PPARG (0.48) | MCHR1L3MBTL1MAPTRAB9ACYP3A4 | |
| SCHEMBL10463121 | 0.96 | PPARG (0.48) | MCHR1L3MBTL1MAPTRAB9ACYP3A4 | |
| SCHEMBL10462806 | 0.96 | PPARG (0.48) | MCHR1L3MBTL1MAPTRAB9ACYP3A4 | |
| SCHEMBL10462372 | 0.95 | PPARG (0.49) | MCHR1L3MBTL1MAPTRAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4913837-A | Heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-03 | — | — | US | disclosed |