Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659280 | 0.93 | TBXA2R (0.70) | ALDH1A1TBXA2RTBXAS1MAPTPRMT1 | |
| SCHEMBL10460529 | 0.89 | ALDH1A1 (0.72) | ALDH1A1TP53GAATBXA2RTBXAS1 | |
| SCHEMBL10462267 | 0.88 | TBXA2R (0.67) | ALDH1A1TBXA2RTBXAS1MAPTPRMT1 | |
| SCHEMBL10463575 | 0.88 | ALDH1A1 (0.61) | ALDH1A1TP53GAATBXA2RPRMT1 | |
| SCHEMBL10463304 | 0.85 | TBXA2R (0.55) | ALDH1A1TP53TBXA2RTBXAS1PRMT1 | |
| SCHEMBL10461595 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TP53GAATBXA2RTBXAS1 | |
| SCHEMBL9661163 | 0.83 | TBXA2R (0.74) | ALDH1A1TP53GAATBXA2RTBXAS1 | |
| SCHEMBL9777971 | 0.81 | TBXA2R (0.59) | ALDH1A1TBXA2RTBXAS1MAPTPRMT1 | |
| SCHEMBL10463031 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TBXA2RTBXAS1MAPTPRMT1 | |
| SCHEMBL9659259 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TBXA2RTBXAS1MAPTPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | claimed |
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |