Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219224 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL10462540 | 0.80 | CYP4Z1 (0.41) | SMN1; SMN2CYP4Z1ALDH1A1MAPTNPC1 | |
| SCHEMBL2384365 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL28673281 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL13492121 | 0.77 | GAA (0.48) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL9202564 | 0.77 | HSP90AB1 (0.66) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL68851 | 0.76 | CYP4Z1 (0.62) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL24541184 | 0.76 | KDM4E (0.53) | SMN1; SMN2CYP4Z1ALDH1A1MAPTNPC1 | |
| SCHEMBL6367851 | 0.76 | MAPT (0.51) | SMN1; SMN2CYP4Z1GAAMAPTRAB9A | |
| SCHEMBL2381215 | 0.76 | MAOB (0.44) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906662-A | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-03-06 | — | — | US | disclosed |