Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463184 | 0.86 | MAPT (0.52) | MAPTPOLBL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL13497817 | 0.85 | MAPT (0.53) | MAPTPOLBHCAR3L3MBTL1ALDH1A1 | |
| SCHEMBL7669945 | 0.83 | MAPT (0.55) | MAPTPOLBPKML3MBTL1ALDH1A1 | |
| SCHEMBL7671343 | 0.83 | MAPT (0.50) | MAPTPOLBL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL10463734 | 0.82 | LMNA (0.69) | MAPTPOLBHCAR3L3MBTL1ALDH1A1 | |
| SCHEMBL15239673 | 0.81 | MAPT (0.61) | MAPTPOLBHCAR3PKML3MBTL1 | |
| SCHEMBL29959789 | 0.78 | MAPT (0.60) | MAPTPOLBHCAR3PKML3MBTL1 | |
| SCHEMBL14334902 | 0.78 | MAPT (0.60) | MAPTPOLBHCAR3PKML3MBTL1 | |
| SCHEMBL2923713 | 0.77 | MAPT (0.57) | MAPTPOLBHCAR3L3MBTL1ALDH1A1 | |
| SCHEMBL13497816 | 0.77 | MAPT (0.53) | MAPTPOLBHCAR3L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904276-A | Nitroaminophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate nitroaminobenzenes and their use in dyeing keratinous fibres | L'OREAL (FR) | 1990-02-27 | — | — | US | disclosed |
| US-4749379-A | HAIR DYES | L'OREAL (FR) | 1988-06-07 | — | — | US | disclosed |