Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | SCNN1A | P37088 | 13/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462678 | 0.81 | SCNN1A (0.41) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| SCHEMBL1441745 | 0.80 | SCNN1A (0.48) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| SCHEMBL16541800 | 0.79 | SCNN1A (0.53) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| SCHEMBL10461270 | 0.79 | SCNN1A (0.43) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| SCHEMBL7293267 | 0.78 | SCNN1A (0.44) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| SCHEMBL10462647 | 0.78 | MEN1 (0.44) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10334228 | 0.77 | SCNN1A (0.43) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| SCHEMBL1429031 | 0.77 | SCNN1A (0.50) | PLAUSCNN1AGRM5ALDH1A1KDM4E | |
| SCHEMBL10965516 | 0.76 | PLAU (0.54) | PLAUSCNN1AGRM5KCNH2ALDH1A1 | |
| SCHEMBL1429125 | 0.76 | SCNN1A (0.44) | PLAUSCNN1AGRM5KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906633-A | Pyrazine amides | ICI AMERICAS INC. (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0293171-A1 | Pyrazinamide derivatives | ICI AMERICAS INC. (US) | 1988-11-30 | — | — | EP | disclosed |