Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464447 | 0.91 | TDP1 (0.55) | ESR1POLBESR2CTDSP1TDP1 | |
| SCHEMBL10462862 | 0.81 | TSHR (0.55) | ESR1POLBESR2CTDSP1TDP1 | |
| SCHEMBL10463466 | 0.81 | TDP1 (0.55) | TDP1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5416139 | 0.81 | CYP1A2 (0.68) | ESR1POLBESR2CTDSP1TDP1 | |
| SCHEMBL10464445 | 0.80 | TDP1 (0.51) | ESR1POLBESR2CTDSP1TDP1 | |
| SCHEMBL10463227 | 0.80 | TDP1 (0.53) | ESR1POLBESR2CTDSP1TDP1 | |
| SCHEMBL10464015 | 0.79 | MRGPRX4 (0.50) | CYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL4887815 | 0.79 | ESR1 (0.72) | ESR1POLBESR2CTDSP1TDP1 | |
| SCHEMBL10463975 | 0.78 | TDP1 (0.64) | TDP1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10463436 | 0.78 | TDP1 (0.54) | ESR1POLBESR2CTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902334-A | HERBICIDES | TEIJIN LIMITED (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0149034-A2 | Regulation of plant metalbolism by alpha,beta- or beta,gamma-unsaturated carboxylic acids or derivatives thereof | TEIJIN LIMITED (JP) | 1985-07-24 | — | — | EP | disclosed |