SCHEMBL4887815

SCHEMBL4887815

Cc1cc(Cl)ccc1OCC(=O)OC(C)C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.72
POLB P06746 1/20 0.72
ESR2 Q92731 1/20 0.72
CTDSP1 Q9GZU7 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
MAPT P10636 3/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2C9 P11712 1/20 0.64
HIF1A Q16665 1/20 0.64
GAA P10253 2/20 0.56
LMNA P02545 4/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
NPC1 O15118 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
TSHR P16473 2/20 0.54
HPGD P15428 2/20 0.54
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
NPSR1 Q6W5P4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29860787 0.87 MAPT (0.67) ESR1POLBESR2CTDSP1TDP1
SCHEMBL158457 0.87 MAPT (0.67) ESR1POLBESR2CTDSP1TDP1
Ammonia Solution, Strong SCHEMBL29010268 0.85 MAPT (0.65) ESR1POLBESR2CTDSP1TDP1
SCHEMBL28681553 0.85 ESR1 (0.64) ESR1POLBESR2CTDSP1TDP1
SCHEMBL3006207 0.84 ESR1 (0.56) ESR1POLBESR2CTDSP1TDP1
SCHEMBL13856582 0.84 ESR1 (1.00) ESR1POLBESR2CTDSP1TDP1
SCHEMBL3003324 0.84 ESR1 (0.62) ESR1POLBESR2CTDSP1TDP1
SCHEMBL27351928 0.83 CYP1A2 (0.69) ESR1POLBESR2CTDSP1TDP1
SCHEMBL4887579 0.83 CYP1A2 (0.69) ESR1POLBESR2CTDSP1TDP1
SCHEMBL4883831 0.83 TDP1 (0.62) ESR1POLBESR2CTDSP1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337017-A1 HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS Bayer Aktiengesellschaft (DE) 2024-03-20 EP claimed
WO-2022152728-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2022-07-21 WO claimed
US-20080242544-A1 Phytoactive Composition MICAP PLC (GB) 2008-10-02 US claimed
EP-1750504-A1 PHYTOACTIVE COMPOSITION MICAP PLC. (GB) 2007-02-14 EP claimed
WO-2005102045-A1 PHYTOACTIVE COMPOSITION MICAP PLC (GB) 2005-11-03 WO claimed
CN-111356684-B Herbicidal pyridyl ethers 巴斯夫欧洲公司 2025-03-28 CN disclosed
US-20250024837-A1 PESTICIDE SYSTEM BANISH, MICHELE 2025-01-23 US disclosed
JP-2024166574-A HERBICIDE COMPOSITION AND METHOD FOR CONTROLLING HARMFUL WEEDS 株式会社エス・ディー・エス バイオテック 2024-11-29 JP disclosed
CN-118765921-A Herbicide composition 住友化学株式会社 2024-10-15 CN disclosed
WO-2024209996-A1 METHOD FOR CONTROLLING HERBICIDE-RESISTANT WEEDS 住友化学株式会社 2024-10-10 WO disclosed
CN-118632626-A (1, 4, 5-Trisubstituted-1H-pyrazol-3-yl) oxy-2-alkoxythioalkyl acids and derivatives thereof, salts thereof and use thereof as herbicidal agents 拜耳公司 2024-09-10 CN disclosed
CN-114249710-B Herbicidal uracil pyridines 巴斯夫欧洲公司 2024-07-23 CN disclosed
WO-2021001273-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2021-01-07 WO disclosed
WO-2020114932-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2020-06-11 WO disclosed
WO-2020114934-A1 HERBICIDE COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2020-06-11 WO disclosed
US-20080242544-A1 Phytoactive Composition MICAP PLC (GB) 2008-10-02 US disclosed
US-20070135307-A1 Inhibition of tuber sprouting ACETO AGRICULTURAL CHEMICALS CORP. (US) 2007-06-14 US disclosed
WO-2007044200-A2 INHIBITION OF TUBER SPROUTING ACETO AGRICULTURAL CHEMICALS CORPORATION (US) 2007-04-19 WO disclosed
EP-1750504-A1 PHYTOACTIVE COMPOSITION MICAP PLC. (GB) 2007-02-14 EP disclosed
WO-2005102045-A1 PHYTOACTIVE COMPOSITION MICAP PLC (GB) 2005-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135307-A1 Inhibition of tuber sprouting PF4, PDGFA, PDGFRB ESR1 2883/4885POLB 2343/4885ESR2 1638/4885
US-20080242544-A1 Phytoactive Composition PNMT, ACHE, TACR1 ESR1 259/4885POLB 4089/4885ESR2 141/4885
US-20250024837-A1 PESTICIDE SYSTEM ACHE, PFAS, FPGS ESR1 1281/4885POLB 898/4885ESR2 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.