Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317930 | 1.00 | MALT1 (0.47) | MALT1SYKKCNA5PCSK9UTS2R | |
| SCHEMBL10463312 | 0.88 | MALT1 (0.51) | MALT1KCNA5UTS2RTPSAB1TPSD1 | |
| SCHEMBL10463311 | 0.85 | SYK (0.46) | MALT1SYKKCNA5PCSK9UTS2R | |
| SCHEMBL10464693 | 0.83 | MALT1 (0.44) | MALT1SYKKCNA5PCSK9UTS2R | |
| SCHEMBL19893985 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL19893990 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL18553075 | 0.80 | MALT1 (0.42) | MALT1SYKKCNA5UTS2RTPSAB1 | |
| SCHEMBL20974085 | 0.80 | MALT1 (0.50) | MALT1SYKKCNA5PCSK9UTS2R | |
| SCHEMBL6404075 | 0.80 | PTPRC (0.41) | PTPRC | |
| SCHEMBL30135170 | 0.80 | MALT1 (0.47) | MALT1SYKKCNA5PCSK9TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943567-A | EFFECTIVE AGAINST PSEUDOMONAS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0293771-A2 | Cephalosporin compound and pharmaceutical composition thereof | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |