Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462415 | 0.96 | KMT2A (0.42) | HPGDKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10463700 | 0.94 | KMT2A (0.41) | HPGDKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10460643 | 0.92 | HPGD (0.51) | HPGDKMT2AMTHFD2ALDH1A1KDM4E | |
| SCHEMBL10462655 | 0.90 | HPGD (0.50) | HPGDKMT2AMTHFD2ALDH1A1KDM4E | |
| SCHEMBL10460463 | 0.90 | KMT2A (0.46) | KMT2AMEN1DHODHSMN1; SMN2TP53 | |
| SCHEMBL10463389 | 0.88 | HPGD (0.46) | HPGDKMT2AMEN1MTHFD2DHODH | |
| SCHEMBL10462125 | 0.86 | HPGD (0.44) | HPGDKMT2AMEN1MTHFD2DHODH | |
| SCHEMBL10462144 | 0.84 | KDM4C (0.42) | HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL10463699 | 0.82 | DHODH (0.39) | HPGDDHODH | |
| SCHEMBL10596774 | 0.82 | ABCB1 (0.40) | HPGDKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |