Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462655 | 0.98 | HPGD (0.50) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL10463389 | 0.93 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL10462125 | 0.92 | HPGD (0.44) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL10463516 | 0.92 | HPGD (0.44) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL10463383 | 0.86 | USP2 (0.42) | HPGDALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10462205 | 0.86 | GABRA1 (0.53) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL10462415 | 0.86 | KMT2A (0.42) | HPGDALDH1A1KDM4EATML3MBTL1 | |
| SCHEMBL10462654 | 0.86 | HPGD (0.48) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL10462369 | 0.85 | USP2 (0.41) | HPGDALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10463700 | 0.85 | KMT2A (0.41) | HPGDALDH1A1KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |