Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462636 | 0.87 | CYP2C19 (0.42) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10462127 | 0.86 | CYP2C19 (0.41) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10462642 | 0.86 | BCL2L1 (0.41) | KMT2AMEN1BCL2L1NPC1RAB9A | |
| SCHEMBL10462656 | 0.78 | LMNA (0.44) | KMT2ABCL2L1NPC1RAB9AMAPT | |
| SCHEMBL9330602 | 0.77 | KMT2A (0.76) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10461757 | 0.77 | LMNA (0.43) | KMT2ABCL2L1NPC1RAB9AMAPT | |
| SCHEMBL2214969 | 0.76 | CYP1A2 (0.45) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL9331283 | 0.75 | CYP2C19 (0.42) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10462126 | 0.75 | CYP2C19 (0.38) | KMT2AMEN1BCL2L1NPC1RAB9A | |
| SCHEMBL10463094 | 0.75 | CYP2C19 (0.42) | NPC1RAB9AMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |