Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869764 | 0.82 | CRHR1 (0.36) | CRHR1EGFR | |
| SCHEMBL9524967 | 0.81 | CRHR1 (0.36) | CRHR1EGFR | |
| SCHEMBL9523084 | 0.80 | EGFR (0.43) | CRHR1BCL2BCL2L1MCL1EGFR | |
| SCHEMBL17085318 | 0.77 | GALR3 (0.54) | EGFR | |
| SCHEMBL15684929 | 0.76 | CNR1 (0.48) | IDH1TTBK1EGFR | |
| SCHEMBL9523322 | 0.76 | TTBK1 (0.41) | CRHR1MCL1TTBK1TTBK2ALDH1A1 | |
| SCHEMBL9471998 | 0.76 | PIK3CD (0.51) | LTA4HALDH1A1 | |
| SCHEMBL9084666 | 0.76 | PTGER4 (0.40) | CRHR1IDH1BCL2BCL2L1MCL1 | |
| Oxalic Acid SCHEMBL9523891 | 0.76 | RPS6KB1 (0.45) | CRHR1BCL2BCL2L1MCL1EGFR | |
| SCHEMBL9728933 | 0.75 | IDH1 (0.37) | CRHR1KDRIDH1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895849-A | Aralkylaminopyrimidine compounds which are useful as for producing thereof and insecticides | UBE INDUSTRIES, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |