Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462636 | 0.82 | CYP2C19 (0.42) | HSD17B10CYP2C19MAPTHTTHPGD | |
| SCHEMBL9331283 | 0.82 | CYP2C19 (0.42) | HSD17B10CYP2C19LMNAMAPTHTT | |
| SCHEMBL10462127 | 0.81 | CYP2C19 (0.41) | HSD17B10CYP2C19MAPTHTTHPGD | |
| SCHEMBL10462126 | 0.79 | CYP2C19 (0.38) | HSD17B10CYP2C19LMNAMAPTHTT | |
| SCHEMBL2214969 | 0.76 | CYP1A2 (0.45) | CYP2C19MAPTHTTHPGDALDH1A1 | |
| SCHEMBL10463094 | 0.75 | CYP2C19 (0.42) | HSD17B10CYP2C19LMNAMAPTHTT | |
| SCHEMBL10461984 | 0.73 | CYP2C19 (0.41) | HSD17B10CYP2C19LMNAMAPTHTT | |
| SCHEMBL10854437 | 0.73 | ADORA2B (0.45) | HSD17B10LMNAMAPTHPGDALDH1A1 | |
| SCHEMBL10461983 | 0.71 | CYP2C19 (0.39) | HSD17B10CYP2C19LMNAMAPTHTT | |
| SCHEMBL9331349 | 0.71 | CYP2C19 (0.44) | HSD17B10CYP2C19LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |
| EP-0040082-B1 | NOVEL SUBSTITUTED OXONICOTINATES, THEIR USE AS PLANT GROWTH REGULATORS AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| EP-0040082-A1 | Novel substituted oxonicotinates, their use as plant growth regulators and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1981-11-18 | — | — | EP | disclosed |