Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826865 | 0.84 | ALOX15 (0.41) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL13375033 | 0.76 | NPC1 (0.41) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL11747703 | 0.75 | — | — | |
| SCHEMBL19350346 | 0.73 | — | — | |
| SCHEMBL9901789 | 0.69 | TYK2 (0.45) | NPC1RAB9AKMT2A | |
| SCHEMBL28771024 | 0.68 | SMN1; SMN2 (0.35) | ALOX15RAB9ASMN1; SMN2HCAR2CYP1A2 | |
| SCHEMBL9125217 | 0.68 | BRD4 (0.39) | ALOX15NPC1RAB9ASMN1; SMN2HCAR2 | |
| SCHEMBL10275853 | 0.67 | PARP1 (0.44) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL1210909 | 0.66 | HCAR2 (0.42) | NPC1RAB9AL3MBTL1HCAR2 | |
| SCHEMBL2325777 | 0.64 | KDM6B (0.41) | LMNAKMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946842-A | BRONCHODILATOR AGENTS; PHOSPHODIESTERASE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-08-07 | — | — | US | disclosed |