Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 17/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522996 | 0.86 | PTAFR (0.68) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9525269 | 0.86 | PTAFR (0.68) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9522421 | 0.86 | PTAFR (0.68) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9522376 | 0.86 | PTAFR (0.68) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9669103 | 0.85 | PTAFR (0.60) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| SCHEMBL10462569 | 0.85 | PTAFR (0.81) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9525884 | 0.85 | PTAFR (0.81) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9525077 | 0.85 | PTAFR (0.81) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9403079 | 0.85 | PTAFR (0.81) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10464347 | 0.85 | PTAFR (0.81) | PTAFROPRK1PDE4DCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960770-A | Vasodilating agents, cardiovascular disorder | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0315698-A1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |