Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282341 | 0.80 | IDO1 (0.58) | IDO1NAPRTKDM4E | |
| SCHEMBL10461634 | 0.77 | CYP1A1 (0.42) | IDO1PDE3BPDE3A | |
| SCHEMBL10461635 | 0.77 | CYP1A1 (0.42) | IDO1PDE3BPDE3A | |
| SCHEMBL26220113 | 0.74 | IDO1 (1.00) | IDO1 | |
| SCHEMBL7350662 | 0.73 | CA12 (0.49) | PDE3BPDE3AKDM4E | |
| SCHEMBL7348389 | 0.73 | ALDH1A1 (0.54) | PDE3BPDE3AKDM4E | |
| SCHEMBL10464308 | 0.72 | CYP1A1 (0.42) | PDE3BPDE3AKDM4EHSD17B10 | |
| SCHEMBL10464309 | 0.72 | CYP1A1 (0.42) | PDE3BPDE3AKDM4EHSD17B10 | |
| SCHEMBL17672056 | 0.72 | NAPRT (0.65) | IDO1NAPRT | |
| SCHEMBL31326722 | 0.72 | NAPRT (0.65) | IDO1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921862-A | Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4792561-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |