Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14124050 | 0.77 | HMGB1 (0.76) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL10464280 | 0.77 | HMGB1 (0.47) | HMGB1CXCL12 | |
| SCHEMBL9755153 | 0.71 | HMGB1 (1.00) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL15861939 | 0.71 | PLA2G2A (0.43) | THRATHRBS1PR3 | |
| SCHEMBL7782524 | 0.71 | HMGB1 (0.63) | HMGB1CXCL12PPARGKAT8 | |
| SCHEMBL7783721 | 0.71 | HMGB1 (0.63) | HMGB1CXCL12PPARGKAT8 | |
| SCHEMBL334544 | 0.71 | HMGB1 (0.63) | HMGB1CXCL12PPARGKAT8 | |
| SCHEMBL11778156 | 0.70 | HMGB1 (0.61) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL10463125 | 0.70 | KAT8 (0.57) | PTPN1PTPN6THRATHRBS1PR3 | |
| SCHEMBL10461267 | 0.70 | KAT8 (0.57) | PTPN1PTPN6THRATHRBS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920091-A | CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-24 | — | — | US | disclosed |