Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | IDH2 | P48735 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876936 | 0.87 | VCP (0.61) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL14069823 | 0.84 | MAPT (0.59) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL28007623 | 0.83 | VCP (0.54) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL29274280 | 0.81 | VCP (0.63) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL30956254 | 0.81 | VCP (0.63) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL23539792 | 0.80 | VCP (0.65) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL23540119 | 0.80 | VCP (0.62) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL30041339 | 0.80 | VCP (0.62) | VCPMAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL18342170 | 0.80 | MEN1 (0.53) | MAPTMAPK1HTTMEN1KMT2A | |
| SCHEMBL10464778 | 0.78 | GAA (0.57) | VCPMAPTNPSR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |