Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104961 | 0.87 | ALDH1A1 (0.71) | ALDH1A1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL12920008 | 0.81 | ALDH1A1 (0.72) | ALDH1A1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10495198 | 0.76 | ALDH1A1 (0.89) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL23080824 | 0.76 | PHGDH (0.59) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL10464492 | 0.75 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10464493 | 0.75 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10464490 | 0.75 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14358433 | 0.75 | PHGDH (0.67) | ALDH1A1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL14361896 | 0.75 | PHGDH (0.67) | ALDH1A1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10720943 | 0.74 | PHGDH (0.81) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929635-A | WOUND HEALING AGENTS, SKIN DISORDERS | LABORATOIRES CHAUVIN-BLACHE (FR) | 1990-05-29 | — | — | US | disclosed |