Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421452 | 0.99 | RECQL (0.50) | PTPN7TDP1MEN1KMT2ARECQL | |
| SCHEMBL8734309 | 0.83 | FAAH (0.59) | MEN1KMT2AALDH1A1FAAHMAPK1 | |
| SCHEMBL9407886 | 0.76 | CNR2 (0.63) | TDP1ALDH1A1BLMHPGDFAAH | |
| SCHEMBL9489137 | 0.75 | SELP (0.56) | PTPN7TDP1MEN1KMT2ARECQL | |
| SCHEMBL9489135 | 0.74 | EPHX2 (0.53) | PTPN7TDP1MEN1KMT2ARECQL | |
| SCHEMBL9421450 | 0.74 | SELP (0.58) | PTPN7TDP1MEN1KMT2ARECQL | |
| SCHEMBL9489747 | 0.74 | SELP (0.73) | PTPN7TDP1MEN1KMT2ARECQL | |
| SCHEMBL9421446 | 0.73 | EPHX2 (0.55) | PTPN7TDP1MEN1KMT2ARECQL | |
| SCHEMBL9649630 | 0.73 | KMT2A (0.36) | TDP1MEN1KMT2AALDH1A1BLM | |
| SCHEMBL9419241 | 0.73 | PTPN7 (0.50) | PTPN7TDP1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916136-A | LIPOXYGENASE AND CYCLOOXYGENASE INHIBITORS | Centre International de Recherches Dermatologioues C.I.R.D. (FR) | 1990-04-10 | — | — | US | claimed |
| US-4916136-A | LIPOXYGENASE AND CYCLOOXYGENASE INHIBITORS | Centre International de Recherches Dermatologioues C.I.R.D. (FR) | 1990-04-10 | — | — | US | disclosed |