Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475461 | 0.76 | NPSR1 (0.47) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL75883 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL28148401 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL75885 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| Urea SCHEMBL23005263 | 0.73 | NPSR1 (0.61) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL28023499 | 0.73 | NPSR1 (0.61) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| Water SCHEMBL27782253 | 0.73 | NPSR1 (0.61) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| Hydrogen Sulfide SCHEMBL28272945 | 0.73 | NPSR1 (0.61) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL11208738 | 0.73 | NPSR1 (0.42) | NPSR1ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL10912480 | 0.72 | NPSR1 (0.41) | NPSR1ALDH1A1POLBNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933352-A | Bi-functional carbamates of 2-ureado-pyridine compounds | THEODOROPULOS SPYROS (US) | 1990-06-12 | — | — | US | disclosed |