Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726837 | 0.89 | HTT (0.53) | NPSR1HTTTP53TSHRALDH1A1 | |
| SCHEMBL28021427 | 0.87 | HTT (0.43) | NPSR1HTTTP53TSHRALDH1A1 | |
| SCHEMBL28021882 | 0.87 | ALDH1A1 (0.45) | NPSR1HTTPTGIRTP53ALDH1A1 | |
| SCHEMBL28021440 | 0.87 | HTT (0.43) | NPSR1HTTPTGIRTP53TSHR | |
| SCHEMBL10855054 | 0.85 | NPSR1 (0.50) | NPSR1HTTPTGIRTP53TSHR | |
| SCHEMBL5271141 | 0.85 | MEN1 (0.45) | NPSR1HTTPTGIRTSHRALDH1A1 | |
| SCHEMBL10668533 | 0.84 | NPSR1 (0.63) | NPSR1HTTPTGIRTP53TSHR | |
| SCHEMBL9742065 | 0.83 | NPSR1 (0.50) | NPSR1HTTTSHRALDH1A1POLB | |
| SCHEMBL27511353 | 0.83 | NPC1 (0.42) | NPSR1HTTPTGIRTP53ALDH1A1 | |
| SCHEMBL27551941 | 0.83 | HTT (0.47) | NPSR1HTTPTGIRTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4173701-A | — | — | None | — | — | JP | disclosed |
| JP-58194804-A | — | — | None | — | — | JP | disclosed |
| CN-111072559-B | Construction and application of 2, 6-dibromopyridine oxidation system | 浙江工商大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-111072559-A | Construction and application of 2, 6-dibromopyridine oxidation system | 浙江工商大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-103880738-A | Preparation method of 1-(2-chloro-4-pyridyl)-3-phenylurea | ZHEJIANG TIDE CROP TECHNOLOGY CO LTD | 2014-06-25 | — | — | CN | disclosed |
| CN-103880737-A | Preparation method of 1-(2-chloro-4-pyridyl)-3-phenylurea | ZHEJIANG TIDE CROP TECHNOLOGY CO LTD | 2014-06-25 | — | — | CN | disclosed |
| WO-2010131030-A1 | PYRIDYLUREA DERIVATIVES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS (INFLAMMATION) LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| CN-1626517-A | Method of synthesized pyridyl of substituting ramification in urea class | DALIAN CHEMICAL PHYSICS INST (CN) | 2005-06-15 | — | — | CN | disclosed |
| CN-1181058-C | Process for preparing pyridylphenylureas | 四川省兰月科技开发公司 | 2004-12-22 | — | — | CN | disclosed |
| CN-1156450-C | Process for preparing unsymmetric phenylpyridyl substances | 中国科学院大连化学物理研究所 | 2004-07-07 | — | — | CN | disclosed |
| CN-1368500-A | Process for preparing unsymmetric phenylpyridyl substances | DALIAN CHEMICAL PHYSICS INST (CN) | 2002-09-11 | — | — | CN | disclosed |
| US-6242257-B1 | CUTTING APICAL EXPLANT FROM GERMINATED COTTON SEEDLING, CULTURING FOR SHOOT PROLIFERATION IN MEDIUM FREE OF AUXIN AND SUCROSE, HARVESTING SHOOTS, THEN CULTURING EACH SHOOT IN SECOND MEDIUM; EFFICIENT PROCESS FOR GENETIC ENGINEERING | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2001-06-05 | — | — | US | disclosed |
| US-6133299-A | ADMINISTERING TO A MAMMAL A COMPOUND SELECTED FROM RALITOLINE, PHENYTOIN, LAMOTRIGINE, CARBAMAZEPINE, LIDOCAINE OR TETRODOTOXIN; TREATING DISEASE SUCH AS STROKE, ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, PARKINSON'S DISEASE | WARNER-LAMBERT COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-5569765-A | 2-anilinopyridine pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5453432-A | Anilinopyridines | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| WO-1994018972-A2 | METHODS FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS USING N-(2,6-DISUBSTITUTED AROMATIC)-N'-PYRIDINYL UREAS AND OTHER ANTICONVULSANT COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1994-09-01 | — | — | WO | disclosed |
| US-5154751-A | HERBICIDAL UREA COMPOUNDS AND COMPOSITIONS | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| JP-H04173701-A | CHEMICAL INJURY-MITIGATIVE AGENT FOR PADDY HERBICIDE | HOKKO CHEM IND CO LTD | 1992-06-22 | — | — | JP | disclosed |
| EP-0233040-A2 | Stigma of crocus sativus L. and method for the production thereof | AJINOMOTO CO., INC. (JP) | 1987-08-19 | — | — | EP | disclosed |
| JP-S58194804-A | AGENT FOR INCREASING YIELD OF POTATO AND TARO | OKAMOTO TOSHIHIKO | 1983-11-12 | — | — | JP | disclosed |