Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 16/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | FPR3 | P25089 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | GPR183 | P32249 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762631 | 0.88 | ADRB2 (0.74) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL10462758 | 0.85 | ADRB2 (0.77) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL10462914 | 0.84 | ADRB2 (0.61) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL10464559 | 0.84 | ADRB2 (0.61) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL10709904 | 0.83 | ADRB2 (0.59) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL9762696 | 0.83 | ADRB2 (0.73) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL9763423 | 0.81 | ADRB2 (0.72) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL4810435 | 0.80 | ADRB2 (0.80) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL9763391 | 0.80 | ADRB2 (0.77) | ADRB2ADRB3ADRB1KDM4EHTR1A | |
| SCHEMBL9762523 | 0.80 | ADRB2 (0.71) | ADRB2ADRB3ADRB1KDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908386-A | Pharmaceuticals | GLAXO GROUP LIMITED (GB) | 1990-03-13 | — | — | US | disclosed |
| EP-0220054-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1987-04-29 | — | — | EP | disclosed |