Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465311 | 1.00 | OPRM1 (0.63) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10465312 | 1.00 | OPRM1 (0.63) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10464363 | 0.92 | OPRM1 (0.67) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10464365 | 0.92 | OPRM1 (0.67) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10464364 | 0.92 | OPRM1 (0.67) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10464822 | 0.85 | OPRM1 (0.56) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10464823 | 0.85 | OPRM1 (0.56) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10464824 | 0.85 | OPRM1 (0.56) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10462669 | 0.83 | OPRM1 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10462667 | 0.83 | OPRM1 (0.57) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916142-A | N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics | BOC, INC. (US) | 1990-04-10 | — | — | US | claimed |
| US-4954506-A | ANALGESICS, NARCOTIC ANTAGONISTS | BOC, INC. (US) | 1990-09-04 | — | — | US | disclosed |
| US-4916142-A | N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics | BOC, INC. (US) | 1990-04-10 | — | — | US | disclosed |
| US-4912109-A | Narcotic antagonist | BOC, INC. (US) | 1990-03-27 | — | — | US | disclosed |